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Clinical trials information for Sponsors

The Trials Accelerator provides the infrastructure to support Sponsors with delivery of commercial and academic CF clinical trials in the UK, along with the platform to enable the CF community to gain access to these trials. Our national team of Trial Coordinators based at our participating centres act as a single point of contact to support Sponsors with feasibility, set-up and delivery of high-priority CF clinical trials.


Participating centres

43 paediatric and adult CF centres form the Trials Accelerator network. Our network of centres works collaboratively to help people with CF from all over the UK access a range of new therapies being developed for CF through taking part in clinical trials. You can read more about our centres and who they are here.

Download our Sponsors brochure

Our Sponsors brochure outlines how the Trials Accelerator can support Sponsors who have a CF therapy portfolio.

Download the brochure

Commercial ‘Involvement’

‘Patient & Public Involvement’ (PPI) is regarded as a highly important component of the UK regulatory process, with the UK Health Research Authority (HRA) strongly encouraging all Sponsors to engage with PPI during trial design. It is now widely acknowledged that the inclusion of PPI at all stages of the trials process leads to better recruitment and retention rates.

PPI should be an active and collaborative opportunity for Sponsors and the CF community that allows the community to act as advisers and partners. The Trials Accelerator has an established group of CF representatives (people with CF, and parents of children with CF) ready to share their lived experience to support Sponsors with trial design and delivery.

This PPI group can benefit Sponsors by offering:

  • Access to an engaged and diverse representation of the CF community
  • Focus group discussions via remote technology
  • One-to-one interviews to access a specific knowledge base
  • Protocol reviews by trained CF representatives
  • Review of design and content of Patient Information Sheets and Consent Forms
  • Lay trial summaries and lay result summaries

Maximum benefit can be achieved by initiating PPI at the earliest possible stage, but it does not exclude involving CF representatives in the latter stages of trials even when there has been no PPI previously.

Please review the Trials Accelerator Sponsors Brochure or contact the Trials Accelerator Involvement Manager (lorna.allen@cysticfibrosis.org.uk) for more information.

Trials Tracker

We have created a CF Trials Tracker so that you can easily access the trials that relate to you. Search by genotype or trial type, and save your favourites!

Clinical Trials Accelerator Platform

Find out more about our UK-wide initiative to bring together existing CF centres to improve access, participation and delivery of clinical trials.

Get involved in a trial

Find out how you can get involved in a clinical trial, whether it's reading our clinical trials booklet, checking out our Trials Tracker or looking at other ways to take part.